- Titel
- Review: Use of Autologous Conditioned Serum (ACS) for Osteoarthritis Treatment in Horses
- Untertitel
- A Systematic Review of Clinical Data
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:15-qucosa2-1011247
- Quellenangabe
- Veterinary Sciences : open access journal
Erscheinungsjahr: 2023
Jahrgang: 10
Heft: 12
Seiten: 1-10
E-ISSN: 2306-7381 - Erstveröffentlichung
- 2023
- Abstract (EN)
- Regenerative medicine has emerged as a widely employed therapy for osteoarthritis (OA) and tendon lesions in both veterinary and human medicine. Despite numerous studies having been conducted, definitive outcomes remain elusive. This study seeks to comprehend the evolution of regenerative medicine from in vitro to in vivo studies, focusing on the effectiveness of Autologous Conditioned Serum (ACS) products in treating OA. The study only took into consideration clinical trials using ACS. All relevant articles published in the last two decades have been scrutinized. Despite a plethora of in vitro studies, the positive outcomes of autologous conditioned serum (ACS) products in in vivo settings have not been conclusively demonstrated. Notably, only six studies met the inclusion criteria. One study incorporated a control group, whereas the other five clinical trials were conducted without a control group. Consequently, there exists no definitive evidence supporting the efficacy of ACS therapy. This underscores the need for more controlled trials to draw a firm conclusion about the effectiveness of ACS as an OA treatment in horses, a conclusion that would have potential implications for humans. The current scarcity of controlled studies highlights the imperative for further research to enhance our understanding of ACS therapy’s therapeutic potential in addressing osteoarthritis.
- Andere Ausgabe
- Erstveröffentlichung
DOI: 10.3390/vetsci10120707
Link: https://www.mdpi.com/2306-7381/10/12/707 - Freie Schlagwörter (EN)
- autologous conditioned serum, osteoarthritis, horse, IRAP, joint
- Klassifikation (DDC)
- 630
- Verlag
- MDPI, Basel
- Version / Begutachtungsstatus
- publizierte Version / Verlagsversion
- URN Qucosa
- urn:nbn:de:bsz:15-qucosa2-1011247
- Veröffentlichungsdatum Qucosa
- 17.12.2025
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis
CC BY 4.0