- AutorIn
- Martin Schulz
- Ulrich Laufs
- Titel
- Not obtaining a medication the first time it is prescribed: primary non-adherence to cardiovascular pharmacotherapy
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:15-qucosa2-1032295
- Quellenangabe
- Clinical research in cardiology : official journal of the German Cardiac Society
Erscheinungsjahr: 2023
Jahrgang: 113
Seiten: 1103-1116
E-ISSN: 1861-0684 - Erstveröffentlichung
- 2023
- Abstract (EN)
- Primary medication non-adherence describes the situation when a first prescription for a new medication is never filled. Primary non-adherence is an important, yet understudied aspect of reduced effectiveness of pharmacotherapy. This review summarizes the frequency, impact, reasons, predictors, and interventions regarding primary non-adherence to cardiovascu- lar/cardiometabolic drugs. The current literature reveals a high prevalence of primary non-adherence. The individual risk of primary non-adherence is determined on multiple factors, e.g., primary non-adherence of lipid-lowering drugs is higher compared to antihypertensive medications. However, the overall rate of primary non-adherence is > 10%. Additionally, this review identifies specific areas for research to better understand why patients forgo evidence-based beneficial pharmaco- therapy and to explore targeted interventions. At the same time, measures to reduce primary non-adherence—once proven to be effective—may represent an important new opportunity to reduce cardiovascular diseases.
- Andere Ausgabe
- Erstveröffentlichung
DOI: 10.1007/s00392-023-02230-3
Link: https://link.springer.com/content/pdf/10.1007/s00392-023-02230-3.pdf - Freie Schlagwörter (EN)
- Medication adherence, Primary non-adherence, Initial non-adherence, Cardiovascular disease, Statins
- Klassifikation (DDC)
- 610
- Verlag
- Springer-Medizin-Verl., Heidelberg
- Version / Begutachtungsstatus
- publizierte Version / Verlagsversion
- URN Qucosa
- urn:nbn:de:bsz:15-qucosa2-1032295
- Veröffentlichungsdatum Qucosa
- 19.03.2026
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis