- AutorIn
- H. Lina Schaare
- Maria Blöchl
- Deniz Kumral
- Marie Uhlig
- Lorenz Lemcke
- Sofie L. Valk
- Arno Villringer
- Titel
- Associations between mental health, blood pressure and the development of hypertension
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:15-qucosa2-1060576
- Quellenangabe
- Nature Communications
Erscheinungsjahr: 2023
Jahrgang: 14
ISSN: 2041-1723
Artikelnummer: 1953 - Erstveröffentlichung
- 2023
- Abstract (EN)
- Multiple studies have reported a link between mental health and high blood pressure with mixed or even contradictory findings. Here, we resolve those contradictions and further dissect the cross-sectional and longitudinal relationship between mental health, systolic blood pressure, and hypertension using extensive psychological, medical and neuroimaging data from the UK Biobank. We show that higher systolic blood pressure is associated with fewer depressive symptoms, greater well-being, and lower emotion-related brain activity. Interestingly, impending hypertension is associated with poorer mental health years before HTN is diagnosed. In addition, a stronger baseline association between systolic blood pressure and better mental health was observed in individuals who develop hypertension until follow-up. Overall, our findings offer insights on the complex relationship between mental health, blood pressure, and hypertension, suggesting that—via baroreceptor mechanisms and reinforcement learning—the association of higher blood pressure with better mental health may ultimately contribute to the development of hypertension.
- Andere Ausgabe
- Erstveröffentlichung
Link: https://www.nature.com/articles/s41467-023-37579-6 - Freie Schlagwörter (EN)
- mental health, systolic blood pressure, hypertension (HTN), baroreceptor mechanisms
- Klassifikation (DDC)
- 500
- Verlag
- Nature Publishing Group UK, London
- Version / Begutachtungsstatus
- publizierte Version / Verlagsversion
- URN Qucosa
- urn:nbn:de:bsz:15-qucosa2-1060576
- Veröffentlichungsdatum Qucosa
- 16.07.2026
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis
CC BY 4.0