- Titel
- Association of response time and intermittent hypoxemia in extremely preterm infants
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:15-qucosa2-994778
- Quellenangabe
- Acta Paediatrica
Erscheinungsjahr: 2023
Jahrgang: 112
Heft: 7
Seiten: 1413-1421
ISSN: 0803-5253
E-ISSN: 1651-2227 - Erstveröffentlichung
- 2023
- Abstract (EN)
- Aim: To determine the relationship between medical staff's response time (RT) to oxygen saturation (SpO2) below 80% and the associated time from tactile intervention until SpO2 normalisation (CT). Methods: Time-lapse video and continuous SpO2 were recorded for six consecutive 24 h periods. Regression analyses of RT and SpO2 in association with postmenstrual age (PMA), weight, infant sex and frequency of intermittent hypoxemia (IH). Results: Five hundred and twelve hypoxemia episodes received tactile intervention in 20 extremely preterm infants (gestational age ≤28 weeks, birthweight <1500 g). Median RT was 20.5 s (IQR 16.63–25.50). RT increased with increased IH frequency (p = 0.023) independently of PMA and weight. SpO2 decreased by 3.7% with every 10 s RT (p = 0.039). Time until SpO2 normalisation was strongly associated with RT (β = 0.58, p = 0.042). The association was amplified by lower PMA (p = 0.043). Female preterm infants experienced longer RT than males (p = 0.027). Because the total length of an IH is the sum of RT and CT, preterm infants with low PMA can reach a critical hypoxemia duration of >60 s, even with short RT. Conclusion: The RT is a critical factor that affects the overall time of IH treatments and the depth of desaturation. The consequences of a prolonged RT are worse for more immature preterm infants.
- Andere Ausgabe
- Erstveröffentlichung
DOI: 10.1111/apa.16766 - Freie Schlagwörter (EN)
- intermittent hypoxemia, extremely preterm infants
- Klassifikation (DDC)
- 610
- Verlag
- Wiley, Hoboken
- Version / Begutachtungsstatus
- publizierte Version / Verlagsversion
- URN Qucosa
- urn:nbn:de:bsz:15-qucosa2-994778
- Veröffentlichungsdatum Qucosa
- 06.10.2025
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis
CC BY-NC-ND 4.0